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VEGF

Packing size: 10µg, 100µg

Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF), is a potent mediator of both
angiogenesis and vasculogenesis in the fetus and adult. VEGF is a glycosylated mitogen that specifically acts on endothelial cells
and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and
endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Six forms of human VEGF mRNA encoding VEGF
proteins of 121, 145, 165, 183, 189, and 206 amino acids are produced from a single gene as a result of alternative splicing.
VEGF165 appears to be the major gene product found in human tissue and is the most effective angiogenic factor in the VEGF
family.




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2018-12-31 09:57:24

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